CamDiab receives approval for world-first fully closed-loop insulin delivery

For years, closed-loop technology has promised to ease the burden of type 1 diabetes. Now, a new development from CamDiab Ltd suggests that promise may be moving closer to reality.

Following approval from its notified body, CamDiab has announced progress towards what it describes as the world’s first commercially available fully closed-loop insulin delivery algorithm — a system designed to operate without carbohydrate counting or pre-meal bolusing.

For people living with type 1 diabetes, this marks a potentially significant shift. While existing hybrid closed-loop systems have already transformed glucose management for many, they still rely on users to estimate carbohydrates and intervene before meals. A fully closed-loop system removes that final layer of manual input, aiming to let the algorithm manage insulin delivery entirely in the background.

Reducing the cognitive load

The importance of this development goes beyond time-in-range or HbA1c improvements. Diabetes management is as much a mental challenge as it is a physiological one, and carb counting and bolusing remain among the most demanding daily tasks.

Professor Roman Hovorka, Director at CamDiab, emphasised this human dimension when announcing the approval:

“By removing the need for carb counting and pre-meal bolusing, we can meaningfully reduce diabetes distress and the relentless cognitive load associated with living with type 1 diabetes.”

The goal, he explained, is not only improved clinical outcomes, but technology that better fits into real life — meals that are spontaneous, social situations that feel less medicalised, and fewer moments where diabetes demands attention.

Early experiences: “like being on holiday”

Feedback from participants who trialled the fully closed-loop algorithm in 2024 offers a glimpse of what that future might feel like. One participant described the experience simply:

“I did not have to do anything… it just made my life so much easier. I just felt I was on a holiday.”

That sense of mental relief — even temporarily — is striking, particularly for long-term technology users who are already familiar with closed-loop systems.

How it works

The innovation will be delivered via CamAPS® FX, CamDiab’s interoperable closed-loop app. The system uses an adaptive, self-learning control algorithm, working with compatible continuous glucose monitoring devices and insulin pumps to autonomously calculate and direct insulin delivery.

CamDiab, founded in 2019, has consistently focused on interoperability and personalised medicine, positioning its technology to evolve alongside CGM and pump ecosystems rather than being locked into a single hardware solution.

What happens next?

A pilot of the fully closed-loop algorithm is planned for early 2026, with wider roll-out expected thereafter. While timelines and access will depend on further evaluation and regulatory processes, the approval itself represents a major step towards integrating fully closed-loop insulin delivery into routine type 1 diabetes care.

For the diabetes community, this development raises an exciting possibility: that closed-loop technology may soon move from reducing effort to removing it altogether.

Libre Life will continue to follow how this technology develops — and what it could mean for people living with type 1 diabetes day to day.

Why this matters now

• Hybrid closed loops still rely on users

  Even the most advanced systems require carb counting and pre-meal boluses — tasks that drive much of the daily mental load.

• Diabetes distress is increasingly recognised

  Clinical outcomes are improving, but burnout and cognitive fatigue remain widespread among people living with type 1 diabetes.

• Technology is shifting from control to relief

  This marks a move away from “decision support” towards genuine automation — where diabetes management happens quietly in the background.

• Spontaneity matters

  Meals, social events, travel and exercise are often unpredictable. Removing pre-meal input could make everyday life feel less constrained.

• A signal of what’s coming next

• With a pilot planned for 2026, fully closed-loop systems may soon move from research settings into routine care.